O le fualaau 'kalisiu pantothenate': uiga ma le faaaogaina i vailaau

acid Pantothenic (pepa inumaga - o le fualaau faasaina "pantothenate kalisiu") e aofia ai i le vaega o vitamini B. lenei suauu, suavai optically toaaga, maualuga soluble i le vai, ua faigofie cleaved i lalo o le gaoioiga o le vevela, acids ma alkalis.

acid Pantothenic o loo maua i meaai ma ua synthesized e microflora intestinal (Escherichia). Ina ua uma ona mitiia e ulufale le bloodstream ma ua ave ia i latou uma totoga ma aano o le tino, o loo teuina i totonu o le ate, o se vaega i myocardium, fatugaʻo ma maso skeletal. I le tino, e sili acid e fesootai ma polotini ma se vaega o le CoA (coenzyme A). malepelepe oloa o le fualaau faasaina "kalisiu pantothenate" excreted i le miaga ma feces. E tatau ona fai e sili atu i taimi uma le aofai o acid pantothenic filifilia nai lo mea ulufale atu i le tino i meaai. ua tatau ona totogi lenei i lona tuufaatasia siama.

acid Pantothenic o se vaega o CoA, lea e aofia ai vaega e tolu: o le tiolamina totoe, acid pantothenic, 3-phospho-5adenozin-5-diphosphate. o CoA se elemene autu i metabolism, auai i le faagaoioiga o le faataamilosaga Krebs i le tuufaatasia moni ma oxidation o carbohydrates, lipids, faavaeina glucosamine, acetylcholine, acid hippuric, porphyrins, ma isi

Fualaau faasaina "pantothenate kalisiu" - teisi efuefu samasama po paepae ma se tofo oona, odorless, soluble i le vai. fofo Aqueous o thermally fale o manu, ae vave soloia ai i lalo pe a faailoa atu ia acid ma alkali. ua tuuina atu le sauniuniga mo vailaau o papa, pauta ma fofo i le ipu.

O lona sauniuniga gaoioiga pharmacological "pantothenate kalisiu" faaalia pe a mavae acid pantothenic liua coenzyme A, lea e aiaia ai beta-oxidation, tuufaatasia acid puta, decarboxylation oxidative, ma faaliliuina pyruvic acid ma acetyl ketoglutaric. E fesoasoani o le mitiia o le kulukose i le suʻia ai, e faateleina ai le tulaga o le glycogen i le ate, normalizes le tulaga hormonal o le tino, aemaise lava i le taimi o maitaga.

I le faaletonu o pantothenic acid i le tino o pituitary galuega tauave hormone inhibited, puna adrenal ma pancreas. O le glands adrenal faaitiitia ai le tulaga o homone steroid, lea e tuuina pigmentation o lauulu ma paʻu. faaosoosoina faaletonu Metabolic dermatitis, depigmentation paʻu. suiga Degenerative matauina i le glands adrenal ma pepa solo popole. E mafai foi ona avea momomo faamaopoopo afi, worsen faamai o le fatugao, loto, loto ona ma manava. O le mafuaaga autu lava o faaletonu vitamini o aofaiga lava o lenei vitamini i meaai, o faamaʻi bowel, ma le faaaogaina faaumiumi o fualaau (sulfonamides, fualaau).

O faailoga togafitiga autu o se le lava o le acid pantothenic i le tino - le atuatuvale, vaivai, vaivai, moe fiti, headaches ma le tiga o maso, faafaufau, manavatatā, flushing o le paʻu taofia, papala duodenal. I le faaletonu o vitamini faaitiitia tetee immunological o le tino. E faasaga i lenei talaaga, tele lava ina o loo i ai faamai respiratory.

lava o taimi, fomai faatonuina le fualaau faasaina "kalisiu pantothenate" mo le faatonutonuina o faiga metabolic. Talia i fai medicament polyneuritis, paresthesia, neuralgia, bronchitis, eczema, dermatitis, mu, ulcers trophic, maitaga toxicosis, fatafata vaivai, hypothyroidism, pancreatitis, gastroduodenitis, ma isi Faafomai "kalisiu pantothenate" lelei taliaina e le tino. Mo mafai enteral pulega dyspeptic auga, e parenteral (tui intramuscular) - tiga.

Oversupply o kalisiu (hypercalcemia) e mafai ona tupu ona o dysfunction o le endocrine glands (parathyroid puna). ua faamauina Hypercalcemia i le matutua. e mafai ona faaali hypercalcemia Falemai o vaivaiga aoao, leiloa o tuinanau, o nisi taimi e matauina cramps ma manava masuasua.